Research Groups

Glial Cell Biology

The mammalian nervous system is comprised of a complex array of multiple cell types required for neural function. Supporting cells, comprised by oligodendrocytes, Schwann cells, astrocytes and microglia are the predominant cell types in the vertebrate nervous system and are critical for both neuronal survival and function. Within our department, a core group focuses on the diverse role of glial cells in nervous system development, disease and repair. Ongoing research investigates the cellular and molecular mechanisms responsible for the proliferation, migration and differentiation of glial cells during development; and glia-associated pathology in multiple sclerosis, HIV, Parkinson’s disease, Alzheimer’s disease, aging and head trauma.

Michelle Block

Michelle M. Block Ph.D.
Microglia in neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease.

Jeff Dupree

Jeff L. Dupree, Ph.D.
Neuron-oligodendrocyte interactions in the adult nervous system.

Babette Fuss

Babette Fuss, Ph.D.
Regulation of oligodendrocyte development and myelination by extracellular signals and their downstream targets.

Pamela Knapp

Pamela E. Knapp, Ph.D.
Glial-neuronal interactions during development and during inflammatory CNS disease processes.

Department of Anatomy and Neurobiology Virginia Commonwealth University VCU Medical Center
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