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Plasticity, Development and Circuitry

The mammalian nervous system is characterized by a highly sophisticated network of cell–to-cell interactions. An understanding of the development and function of neural systems is necessary to combat neurological disease and dysfunction. Our faculty examine basic structural and functional mechanisms underlying sensory processing and plasticity at molecular, cellular and network levels. This work has clinical implications for fetal alcohol syndrome, autism, spinal cord damage, epilepsy, dyslexia, deafness and other neurodevelopmental disorders.

Michael Fox

Michael Fox, Ph.D.
Molecular signals regulating synaptic organization.

William Guido

William Guido, Ph.D.
Cellular and molecular mechanisms responsible for the activity dependent refinement of sensory connections.

Kimberle Jacobs

Kimberle Jacobs, Ph.D.
Cortical elements and circuitry that contribute to plasticity of the nervous system.

A. Rory McQuiston

A. Rory McQuiston, Ph.D.
The role of inhibitory interneurons in shaping neural network activity.

Alexandre E. Medina

Alexandre E. Medina, Ph.D.
Alterations in brain development and neuronal plasticity following external insults, e.g., alcohol and medications.

M. Alex Meredith

M. Alex Meredith Ph.D.
Architecture and role of multisensory circuits in normal and deaf cerebral cortex.

Department of Anatomy and Neurobiology Virginia Commonwealth University VCU Medical Center
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